Based on the early, limited mechanistic understanding of acetaminophen hepatotoxicity, which included reactive metabolite formation and hepatic GSH depletion [58, 59], various antidotes with the capacity to replenish hepatic GSH levels were tested
Modulation of oxidative stress as an anticancer strategy
Unlike oral administered, which can cause stomach upset, intravenous offers a preferable option for minimizing discomfort without gastrointestinal side effects
PLoS ONE , 13(6), e0198626
Evolution and diversity of glutaredoxins in photosynthetic organisms
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